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RORα is crucial for attenuated inflammatory response to maintain intestinal homeostasis
Retinoic acid-related orphan receptor α (RORα) functions as a transcription factor for various biological processes, including circadian rhythm, cancer, and metabolism. Here, we generate intestinal epithelial cell (IEC)-specific RORα-deficient (RORα(ΔIEC)) mice and find that RORα is crucial for main...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800319/ https://ncbi.nlm.nih.gov/pubmed/31570593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907595116 |
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