Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress

Pancreatic acinar cells possess very high protein synthetic rates as they need to produce and secrete large amounts of digestive enzymes. Acinar cell damage and dysfunction cause malnutrition and pancreatitis, and inflammation of the exocrine pancreas that promotes development of pancreatic ductal a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Antonucci, Laura, Fagman, Johan B., Kim, Ju Youn, Todoric, Jelena, Gukovsky, Ilya, Mackey, Mason, Ellisman, Mark H., Karin, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653219/
https://ncbi.nlm.nih.gov/pubmed/26512112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519384112
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