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Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress
Pancreatic acinar cells possess very high protein synthetic rates as they need to produce and secrete large amounts of digestive enzymes. Acinar cell damage and dysfunction cause malnutrition and pancreatitis, and inflammation of the exocrine pancreas that promotes development of pancreatic ductal a...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653219/ https://ncbi.nlm.nih.gov/pubmed/26512112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519384112 |
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