RORα is crucial for attenuated inflammatory response to maintain intestinal homeostasis

Retinoic acid-related orphan receptor α (RORα) functions as a transcription factor for various biological processes, including circadian rhythm, cancer, and metabolism. Here, we generate intestinal epithelial cell (IEC)-specific RORα-deficient (RORα(ΔIEC)) mice and find that RORα is crucial for main...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Oh, Se Kyu, Kim, Dongha, Kim, Kyeongkyu, Boo, Kyungjin, Yu, Young Suk, Kim, Ik Soo, Jeon, Yoon, Im, Sun-Kyoung, Lee, Su-Hyung, Lee, Ji Min, Ko, Younhee, Lee, Ho, Park, Daechan, Fang, Sungsoon, Baek, Sung Hee
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800319/
https://ncbi.nlm.nih.gov/pubmed/31570593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907595116
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