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Muscle acetylcholine receptor conversion into chloride conductance at positive potentials by a single mutation

Charge selectivity forms the basis of cellular excitation or inhibition by Cys-loop ligand-gated ion channels (LGICs), and is essential for physiological receptor function. There are no reports of naturally occurring mutations in LGICs associated with the conversion of charge selectivity. Here, we r...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Cetin, Hakan, Epstein, Max, Liu, Wei W., Maxwell, Susan, Rodriguez Cruz, Pedro M., Cossins, Judith, Vincent, Angela, Webster, Richard, Biggin, Philip C., Beeson, David
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800317/
https://ncbi.nlm.nih.gov/pubmed/31570625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908284116
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