Fluorescent 5-Pyrimidine and 8-Purine Nucleosides Modified with an N-Unsubstituted 1,2,3-Triazol-4-yl Moiety

The Cu(I)- or Ag(I)-catalyzed cycloaddition between 8-ethynyladenine or guanine nucleosides and TMSN(3) gave 8-(1-H-1,2,3-triazol-4-yl) nucleosides in good yields. On the other hand, reactions of 5-ethynyluracil or cytosine nucleosides with TMSN(3) led to the chemoselective formation of triazoles vi...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Wen, Zhiwei, Tuttle, Paloma R., Howlader, A. Hasan, Vasilyeva, Anna, Gonzalez, Laura, Tangar, Antonija, Lei, Ruipeng, Laverde, Eduardo E., Liu, Yuan, Miksovska, Jaroslava, Wnuk, Stanislaw F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800167/
https://ncbi.nlm.nih.gov/pubmed/30806513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b03135
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