Demodifying RNA for Transcriptomic Analyses of Archival Formalin-Fixed Paraffin-Embedded Samples

Archival formalin-fixed paraffin-embedded (FFPE) tissue samples offer a vast but largely untapped resource for genomic research. The primary technical issues limiting use of FFPE samples are RNA yield and quality. In this study, we evaluated methods to demodify RNA highly fragmented and crosslinked...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Wehmas, Leah C., Wood, Charles E., Gagne, Remi, Williams, Andrew, Yauk, Carole, Gosink, Mark M., Dalmas, Deidre, Hao, Ruixin, O’Lone, Raegan, Hester, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800129/
https://ncbi.nlm.nih.gov/pubmed/29228314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx278
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