Demodifying RNA for Transcriptomic Analyses of Archival Formalin-Fixed Paraffin-Embedded Samples

Archival formalin-fixed paraffin-embedded (FFPE) tissue samples offer a vast but largely untapped resource for genomic research. The primary technical issues limiting use of FFPE samples are RNA yield and quality. In this study, we evaluated methods to demodify RNA highly fragmented and crosslinked...

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Vydáno v:Toxicol Sci
Hlavní autoři: Wehmas, Leah C., Wood, Charles E., Gagne, Remi, Williams, Andrew, Yauk, Carole, Gosink, Mark M., Dalmas, Deidre, Hao, Ruixin, O’Lone, Raegan, Hester, Susan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800129/
https://ncbi.nlm.nih.gov/pubmed/29228314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx278
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