Case study: Targeted RNA-sequencing of aged formalin-fixed paraffin-embedded samples for understanding chemical mode of action

Formalin-fixed paraffin-embedded (FFPE) samples are the only remaining biological archive for many toxicological and clinical studies, yet their use in genomics has been limited due to nucleic acid damage from formalin fixation. Older FFPE samples with highly degraded RNA pose a particularly difficu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Michael D. Cannizzo, Charles E. Wood, Susan D. Hester, Leah C. Wehmas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-01-01
Colecção:Toxicology Reports
Assuntos:
Formalin-fixed paraffin-embedded (FFPE)
RNA-Seq
TempO-Seq
Dichloroacetic acid
DCA
Benchmark dose (BMD) analysis
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2214750022000956
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados