Lysosomal regulation of extracellular vesicle excretion during D-ribose-induced NLRP3 inflammasome activation in podocytes

The NLRP3 inflammasome is activated in the cytoplasm of cells and its products such as IL-1β are exported through a non-classical ER-Golgi pathway. Several mechanistically distinct models including exocytosis of secretory lysosomes, microvesicles (MVs) and extracellular vehicles (EVs) have been prop...

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Bibliographic Details
Published in:Biochim Biophys Acta Mol Cell Res
Main Authors: Hong, Jinni, Bhat, Owais M., Li, Guangbi, Dempsey, Sara K., Zhang, Qinghua, Ritter, Joseph K., Li, Weiwei, Li, Pin-Lan
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800119/
https://ncbi.nlm.nih.gov/pubmed/30771382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2019.02.007
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