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NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury

The nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome has been implicated in podocyte injury and glomerular sclerosis during hyperhomocysteinemia (hHcys). However, it remains unclear whether the NLRP3 inflammasome can be a therapeutic target for t...

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Podrobná bibliografie
Vydáno v:J Lipid Res
Hlavní autoři: Li, Guangbi, Chen, Zhida, Bhat, Owais M., Zhang, Qinghua, Abais-Battad, Justine M., Conley, Sabena M., Ritter, Joseph K., Li, Pin-Lan
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454504/
https://ncbi.nlm.nih.gov/pubmed/28404641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M072587
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