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3488 A comparison between the Rolling 6 and 3+3 dose escalation study designs for phase 1 clinical trials
OBJECTIVES/SPECIFIC AIMS: The development of new anti-cancer agents for children requires an inherently longer timeline than in adults. The 3+3 study design for Phase 1 dose escalation trials is commonly used to estimate the maximum tolerated dose and assess safety. The Rolling 6 study design was de...
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| Publicado no: | J Clin Transl Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cambridge University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6799314/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.73 |
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