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Topical administration of regorafenib eye drops: phase I dose‐escalation study in healthy volunteers
AIM: Regorafenib is a multikinase inhibitor under investigation for use in neovascular age‐related macular degeneration. In this phase I study, regorafenib eye drops were administered to healthy volunteers to provide information on safety, tolerability and systemic exposure. METHODS: This was a sing...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5903260/ https://ncbi.nlm.nih.gov/pubmed/29315699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13502 |
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