2018 Synaptic vesicle 2 receptors as a novel targets for neuroendocrine cancer therapy

OBJECTIVES/SPECIFIC AIMS: (1) To delineate the function of the heavy-chain receptor binding domain (HCR), a portion of botulinum neurotoxin type A (BoNT/A) and synaptic vesicle 2 (SV2) signaling pathway, which provide a novel multipurpose biologic with potential clinical applications in tumor detect...

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Bibliographic Details
Published in:J Clin Transl Sci
Main Authors: Jaskula-Sztul, Renata, Whitt, Jason D., Ou, Jianfa, Liu, Margaret X., Aburjania, Zviadi, Chen, Herbert
Format: Artigo
Language:Inglês
Published: Cambridge University Press 2018
Subjects:
Basic/Translational Science/Team Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799207/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.125
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