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Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

In an effort to discover viable systemic chemotherapeutic agents for neuroendocrine tumors (NETs), we screened a small library of 18 drug-like compounds obtained from the Velu lab against pulmonary (H727) and thyroid (MZ-CRC-1 and TT) neuroendocrine tumor-derived cell lines. Two potent lead compound...

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Podrobná bibliografie
Vydáno v:Molecules
Hlavní autoři: Aburjania, Zviadi, Whitt, Jason D., Jang, Samuel, Nadkarni, Dwayaja H., Chen, Herbert, Rose, J. Bart, Velu, Sadanandan E., Jaskula-Sztul, Renata
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663375/
https://ncbi.nlm.nih.gov/pubmed/33114525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25214940
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