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2219: Amyotrophic lateral sclerosis, stem cells and TALENted technology

OBJECTIVES/SPECIFIC AIMS: The current treatment for amyotrophic lateral sclerosis (ALS) includes systemic delivery of neurotrophic factors (NTFs). Although this approach may seem theoretically sound, NTF efficacy within the central nervous system (CNS) is largely limited by the blood-brain barrier....

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Détails bibliographiques
Publié dans:J Clin Transl Sci
Auteurs principaux: Kurani, Shaheen, Madigan, Nicolas, Clark, Karl, Ekker, Stephen, Staff, Nathan, Windebank, Anthony
Format: Artigo
Langue:Inglês
Publié: Cambridge University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798916/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.212
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