Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS

Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder with complex biology and significant clinical heterogeneity. Many preclinical and early phase ALS clinical trials have yielded promising results that could not be replicated in larger phase 3 confirmatory trials. One re...

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Vydáno v:Muscle Nerve
Hlavní autoři: Goyal, Namita A., Berry, James D., Windebank, Anthony, Staff, Nathan P., Maragakis, Nicholas J., van den Berg, Leonard H., Genge, Angela, Miller, Robert, Baloh, Robert H., Kern, Ralph, Gothelf, Yael, Lebovits, Chaim, Cudkowicz, Merit
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2020
Témata:
Invited Reviews
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496557/
https://ncbi.nlm.nih.gov/pubmed/31899540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.26801
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