Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS

Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder with complex biology and significant clinical heterogeneity. Many preclinical and early phase ALS clinical trials have yielded promising results that could not be replicated in larger phase 3 confirmatory trials. One re...

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Udgivet i:Muscle Nerve
Main Authors: Goyal, Namita A., Berry, James D., Windebank, Anthony, Staff, Nathan P., Maragakis, Nicholas J., van den Berg, Leonard H., Genge, Angela, Miller, Robert, Baloh, Robert H., Kern, Ralph, Gothelf, Yael, Lebovits, Chaim, Cudkowicz, Merit
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Invited Reviews
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496557/
https://ncbi.nlm.nih.gov/pubmed/31899540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.26801
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