Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS

Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder with complex biology and significant clinical heterogeneity. Many preclinical and early phase ALS clinical trials have yielded promising results that could not be replicated in larger phase 3 confirmatory trials. One re...

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Detalhes bibliográficos
Publicado no:Muscle Nerve
Main Authors: Goyal, Namita A., Berry, James D., Windebank, Anthony, Staff, Nathan P., Maragakis, Nicholas J., van den Berg, Leonard H., Genge, Angela, Miller, Robert, Baloh, Robert H., Kern, Ralph, Gothelf, Yael, Lebovits, Chaim, Cudkowicz, Merit
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Invited Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496557/
https://ncbi.nlm.nih.gov/pubmed/31899540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.26801
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