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2219: Amyotrophic lateral sclerosis, stem cells and TALENted technology

OBJECTIVES/SPECIFIC AIMS: The current treatment for amyotrophic lateral sclerosis (ALS) includes systemic delivery of neurotrophic factors (NTFs). Although this approach may seem theoretically sound, NTF efficacy within the central nervous system (CNS) is largely limited by the blood-brain barrier....

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Pubblicato in:J Clin Transl Sci
Autori principali: Kurani, Shaheen, Madigan, Nicolas, Clark, Karl, Ekker, Stephen, Staff, Nathan, Windebank, Anthony
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cambridge University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798916/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.212
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