To be or not to be pink(1): contradictory findings in an animal model for Parkinson’s disease

The PTEN-induced putative kinase 1 knockout rat (Pink1(−/−)) is marketed as an established model for Parkinson’s disease, characterized by development of motor deficits and progressive degeneration of half the dopaminergic neurons in the substantia nigra pars compacta by 8 months of age. In this stu...

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Dettagli Bibliografici
Pubblicato in:Brain Commun
Autori principali: de Haas, Ria, Heltzel, Lisa C M W, Tax, Denise, van den Broek, Petra, Steenbreker, Hilbert, Verheij, Michel M M, Russel, Frans G M, Orr, Adam L, Nakamura, Ken, Smeitink, Jan A M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798789/
https://ncbi.nlm.nih.gov/pubmed/31667474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcz016
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