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PINK1-Based Screen Shines Light on Autophagy Enhancers for Parkinson’s Disease

In this issue of Cell Chemical Biology, Zhang et al. (2017) report a zebrafish model of Parkinson’s disease (PD), incorporating the PD-protein PINK1 and rotenone, a toxin linked to PD. Using it as a drug-screening platform, they identify trifluoperazine and other piperazine phenothiazines as protect...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Haddad, Dominik, Nakamura, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845914/
https://ncbi.nlm.nih.gov/pubmed/28431223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.04.002
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