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Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson’s disease

Mitochondria are undoubtedly changed in Parkinson’s disease (PD), and mitochondrial functions are disrupted in genetic and pharmacologic models of PD. However, many of these changes might not truly drive neurodegeneration. PD is defined by the particular susceptibility of nigrostriatal dopamine (DA)...

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Udgivet i:FEBS Lett
Main Authors: Haddad, Dominik, Nakamura, Ken
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679488/
https://ncbi.nlm.nih.gov/pubmed/26526613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.10.021
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