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Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson’s disease

Mitochondria are undoubtedly changed in Parkinson’s disease (PD), and mitochondrial functions are disrupted in genetic and pharmacologic models of PD. However, many of these changes might not truly drive neurodegeneration. PD is defined by the particular susceptibility of nigrostriatal dopamine (DA)...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Haddad, Dominik, Nakamura, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679488/
https://ncbi.nlm.nih.gov/pubmed/26526613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.10.021
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