Zebrafish studies identify serotonin receptors mediating antiepileptic activity in Dravet syndrome

Dravet syndrome is a life-threatening early-onset epilepsy not well controlled by antiepileptic drugs. Drugs that modulate serotonin (5-HT) signalling, including clemizole, locaserin, trazodone and fenfluramine, have recently emerged as potential treatment options for Dravet syndrome. To investigate...

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Bibliografiske detaljer
Udgivet i:Brain Commun
Main Authors: Griffin, Aliesha L, Jaishankar, Priyadarshini, Grandjean, Jean-Marc, Olson, Steven H, Renslo, Adam R, Baraban, Scott C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798786/
https://ncbi.nlm.nih.gov/pubmed/31667472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcz008
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