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Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome
Dravet syndrome is a catastrophic childhood epilepsy with early-onset seizures, delayed language and motor development, sleep disturbances, anxiety-like behaviour, severe cognitive deficit and an increased risk of fatality. It is primarily caused by de novo mutations of the SCN1A gene encoding a neu...
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| Vydáno v: | Brain |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6075536/ https://ncbi.nlm.nih.gov/pubmed/28073790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww342 |
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