Preclinical Animal Models for Dravet Syndrome: Seizure Phenotypes, Comorbidities and Drug Screening

Epilepsy is a common chronic neurological disease affecting almost 3 million people in the United States and 50 million people worldwide. Despite availability of more than two dozen FDA-approved anti-epileptic drugs (AEDs), one-third of patients fail to receive adequate seizure control. Specifically...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Griffin, Aliesha, Hamling, Kyla R., Hong, SoonGweon, Anvar, Mana, Lee, Luke P., Baraban, Scott C.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994396/
https://ncbi.nlm.nih.gov/pubmed/29915537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00573
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