3373 Modulation of Hedgehog Signaling Alters Immune Infiltration in Pancreatic Cancer

OBJECTIVES/SPECIFIC AIMS: Pancreatic ductal adenocarcinoma (PDA) has a dismal 5-year survival rate of 9%, making this disease one of the deadliest human malignancies (https://seer.cancer.gov/). Primary barriers to the treatment of pancreatic cancer include extensive stromal interactions and sustaine...

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Foilsithe in:J Clin Transl Sci
Main Authors: Steele, Nina, Irizarry-Negron, Valerie, Sirihorachai, Veerin, Kemp, Samantha, Carpenter, Eileen, Halbrook, Christopher, Lyssiotis, Costas, Bednar, Filip, Frankel, Timothy, Allen, Benjamin, Pasca di Magliano, Marina
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cambridge University Press 2019
Ábhair:
Basic/Translational Science/Team Science
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798673/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.40
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