Inhibition of Hedgehog signaling alters fibroblast composition in pancreatic cancer

PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensive fibroinflammatory stroma, which includes abundant cancer-associated fibroblast (CAF) populations. PDAC CAFs are heterogeneous, but the nature of this heterogeneity is incompletely understood. The Hedge...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Steele, Nina G., Biffi, Giulia, Kemp, Samantha B., Zhang, Yaqing, Drouillard, Donovan, Syu, LiJyun, Hao, Yuan, Oni, Tobiloba E., Brosnan, Erin, Elyada, Ela, Doshi, Abhishek, Hansma, Christa, Espinoza, Carlos, Abbas, Ahmed, The, Stephanie, Irizarry-Negron, Valerie, Halbrook, Christopher J., Franks, Nicole E., Hoffman, Megan T., Brown, Kristee, Carpenter, Eileen S., Nwosu, Zeribe C., Johnson, Craig, Lima, Fatima, Anderson, Michelle A., Park, Youngkyu, Crawford, Howard C., Lyssiotis, Costas A., Frankel, Timothy L., Rao, Arvind, Bednar, Filip, Dlugosz, Andrzej A., Preall, Jonathan B., Tuveson, David A., Allen, Benjamin L., di Magliano, Marina Pasca
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026631/
https://ncbi.nlm.nih.gov/pubmed/33495315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-3715
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