Exploring Plasmodium falciparum Var Gene Expression to Assess Host Selection Pressure on Parasites During Infancy

In sub-Saharan Africa, children below 5 years bear the greatest burden of severe malaria because they lack naturally acquired immunity that develops following repeated exposure to infections by Plasmodium falciparum. Antibodies to the surface of P. falciparum infected erythrocytes (IE) play an impor...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Kivisi, Cheryl A., Muthui, Michelle, Hunt, Martin, Fegan, Greg, Otto, Thomas Dan, Githinji, George, Warimwe, George M., Rance, Richard, Marsh, Kevin, Bull, Peter C., Abdi, Abdirahman I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798654/
https://ncbi.nlm.nih.gov/pubmed/31681266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02328
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