Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria

BACKGROUND: Plasmodium falciparum erythrocyte membrane protein 1(PfEMP1) is a family of variant surface antigens (VSA) that mediate the adhesion of parasite infected erythrocytes to capillary endothelial cells within host tissues. Opinion is divided over the role of PfEMP1 in the widespread endothel...

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Autors principals: Abdi, Abdirahman I, Fegan, Gregory, Muthui, Michelle, Kiragu, Esther, Musyoki, Jennifer N, Opiyo, Michael, Marsh, Kevin, Warimwe, George M, Bull, Peter C
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986854/
https://ncbi.nlm.nih.gov/pubmed/24674301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-170
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