Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria

BACKGROUND: Plasmodium falciparum erythrocyte membrane protein 1(PfEMP1) is a family of variant surface antigens (VSA) that mediate the adhesion of parasite infected erythrocytes to capillary endothelial cells within host tissues. Opinion is divided over the role of PfEMP1 in the widespread endothel...

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Detalhes bibliográficos
Main Authors: Abdi, Abdirahman I, Fegan, Gregory, Muthui, Michelle, Kiragu, Esther, Musyoki, Jennifer N, Opiyo, Michael, Marsh, Kevin, Warimwe, George M, Bull, Peter C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986854/
https://ncbi.nlm.nih.gov/pubmed/24674301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-170
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