Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria

BACKGROUND: Plasmodium falciparum erythrocyte membrane protein 1(PfEMP1) is a family of variant surface antigens (VSA) that mediate the adhesion of parasite infected erythrocytes to capillary endothelial cells within host tissues. Opinion is divided over the role of PfEMP1 in the widespread endothel...

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Autori principali: Abdi, Abdirahman I, Fegan, Gregory, Muthui, Michelle, Kiragu, Esther, Musyoki, Jennifer N, Opiyo, Michael, Marsh, Kevin, Warimwe, George M, Bull, Peter C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986854/
https://ncbi.nlm.nih.gov/pubmed/24674301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-170
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