Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure

BACKGROUND: The PfEMP1 family of Plasmodium falciparum antigens play a key role in pathogenesis of severe malaria through their insertion into the surface of parasite infected erythrocytes, and adhesion to host cells. Previous studies have suggested that parasites expressing PfEMP1 subclasses group...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Abdi, Abdirahman I., Hodgson, Susanne H., Muthui, Michelle K., Kivisi, Cheryl A., Kamuyu, Gathoni, Kimani, Domtila, Hoffman, Stephen L., Juma, Elizabeth, Ogutu, Bernhards, Draper, Simon J., Osier, Faith, Bejon, Philip, Marsh, Kevin, Bull, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569527/
https://ncbi.nlm.nih.gov/pubmed/28835215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2686-0
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