Clinical insights gained by refining the 2016 WHO classification of diffuse gliomas with: EGFR amplification, TERT mutations, PTEN deletion and MGMT methylation

BACKGROUND: Significant advances in the molecular profiling of gliomas, led the 2016 World Health Organization (WHO) Classification to include, for the first-time, molecular biomarkers in glioma diagnosis: IDH mutations and 1p/19q codeletion. Here, we evaluated the effect of this new classification...

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Foilsithe in:BMC Cancer
Main Authors: Brito, Cheila, Azevedo, Ana, Esteves, Susana, Marques, Ana Rita, Martins, Carmo, Costa, Ilda, Mafra, Manuela, Bravo Marques, José M., Roque, Lúcia, Pojo, Marta
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798410/
https://ncbi.nlm.nih.gov/pubmed/31623593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6177-0
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