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COPY NUMBER GAINS IN EGFR AND COPY NUMBER LOSSES IN PTEN ARE COMMON EVENTS IN OSTEOSARCOMA TUMORS
BACKGROUND: Osteosarcoma cell lines and tumors have been shown to express EGFR and harbor amplifications at the EGFR locus. In this study, we further analyze the genomic features of EGFR in osteosarcoma tumors and investigate whether they correlate with PTEN expression and copy number status. METHOD...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529469/ https://ncbi.nlm.nih.gov/pubmed/18704985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.23782 |
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