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CSIG-27. DIFFERENTIAL ELEVATION OF TERT ACTIVITY AND SENSITIVITY TO TEMOZOLOMIDE BY TYPE OF TERT MUTATION IN MGMT PROMOTER-METHYLATED GLIOBLASTOMA
BACKGROUND: Benefit from temozolomide chemotherapy in glioblastoma is essentially limited to patients with tumors that exhibit O(6)-methylguanine DNA methyltransferase (MGMT) promoter methylation. Recent retrospective clinical analyses indicate that the impact of the MGMT status on chemosensitivity...
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| Publicado no: | Neuro Oncol |
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| Principais autores: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216676/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.193 |
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