DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment

BACKGROUND: Ependymal tumors are glial tumors that commonly manifest in children and young adults. Their classification has remained entirely morphological until recently, and surgery and radiotherapy are the main treatment options, especially in adults. Here we sought to correlate DNA methylation p...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Witt, Hendrik, Gramatzki, Dorothee, Hentschel, Bettina, Pajtler, Kristian W, Felsberg, Jörg, Schackert, Gabriele, Löffler, Markus, Capper, David, Sahm, Felix, Sill, Martin, von Deimling, Andreas, Kool, Marcel, Herrlinger, Ulrich, Westphal, Manfred, Pietsch, Torsten, Reifenberger, Guido, Pfister, Stefan M, Tonn, Jörg C, Weller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231197/
https://ncbi.nlm.nih.gov/pubmed/30053291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy118
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