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TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts
PURPOSE: To investigate the molecular pathways that drive thyroid stimulating hormone receptor (TSHR)–induced cellular proliferation in orbital fibroblasts (OFs) from thyroid eye disease (TED) patients. METHODS: Orbital fibroblasts from TED and non-TED patients were treated with TSH and changes in g...
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| Publicat a: | Invest Ophthalmol Vis Sci |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Association for Research in Vision and Ophthalmology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6798326/ https://ncbi.nlm.nih.gov/pubmed/31622470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-27865 |
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