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TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts

PURPOSE: To investigate the molecular pathways that drive thyroid stimulating hormone receptor (TSHR)–induced cellular proliferation in orbital fibroblasts (OFs) from thyroid eye disease (TED) patients. METHODS: Orbital fibroblasts from TED and non-TED patients were treated with TSH and changes in g...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Invest Ophthalmol Vis Sci
Main Authors: Woeller, Collynn F., Roztocil, Elisa, Hammond, Christine, Feldon, Steven E.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Association for Research in Vision and Ophthalmology 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798326/
https://ncbi.nlm.nih.gov/pubmed/31622470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-27865
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