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TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts
PURPOSE: To investigate the molecular pathways that drive thyroid stimulating hormone receptor (TSHR)–induced cellular proliferation in orbital fibroblasts (OFs) from thyroid eye disease (TED) patients. METHODS: Orbital fibroblasts from TED and non-TED patients were treated with TSH and changes in g...
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| Publié dans: | Invest Ophthalmol Vis Sci |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Association for Research in Vision and Ophthalmology
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6798326/ https://ncbi.nlm.nih.gov/pubmed/31622470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-27865 |
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