Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1

Early interactions of influenza A virus (IAV) with respiratory epithelium might determine the outcome of infection. The study of global cellular innate immune responses often masks multiple aspects of the mechanisms by which populations of cells work as organized and heterogeneous systems to defeat...

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Veröffentlicht in:J Virol
Hauptverfasser: Ramos, Irene, Smith, Gregory, Ruf-Zamojski, Frederique, Martínez-Romero, Carles, Fribourg, Miguel, Carbajal, Edwin A., Hartmann, Boris M., Nair, Venugopalan D., Marjanovic, Nada, Monteagudo, Paula L., DeJesus, Veronica A., Mutetwa, Tinaye, Zamojski, Michel, Tan, Gene S., Jayaprakash, Ciriyam, Zaslavsky, Elena, Albrecht, Randy A., Sealfon, Stuart C., García-Sastre, Adolfo, Fernandez-Sesma, Ana
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Cellular Response to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798124/
https://ncbi.nlm.nih.gov/pubmed/31375585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00559-19
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