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Differential Modulation of Innate Immune Responses in Human Primary Cells by Influenza A Viruses Carrying Human or Avian Nonstructural Protein 1

The influenza A virus (IAV) nonstructural protein 1 (NS1) contributes to disease pathogenesis through the inhibition of host innate immune responses. Dendritic cells (DCs) release interferons (IFNs) and proinflammatory cytokines and promote adaptive immunity upon viral infection. In order to charact...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Monteagudo, Paula L., Muñoz-Moreno, Raquel, Fribourg, Miguel, Potla, Uma, Mena, Ignacio, Marjanovic, Nada, Hartmann, Boris M., Sealfon, Stuart C., García-Sastre, Adolfo, Ramos, Irene, Fernández-Sesma, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912104/
https://ncbi.nlm.nih.gov/pubmed/31597767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00999-19
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