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Human APOBEC3G Prevents Emergence of Infectious Endogenous Retrovirus in Mice

Endogenous retroviruses (ERV) are found throughout vertebrate genomes, and failure to silence their activation can have deleterious consequences on the host. Mutation and subsequent disruption of ERV loci is therefore an indispensable component of the cell-intrinsic defenses that maintain the integr...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Treger, Rebecca S., Tokuyama, Maria, Dong, Huiping, Salas-Briceno, Karen, Ross, Susan R., Kong, Yong, Iwasaki, Akiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798113/
https://ncbi.nlm.nih.gov/pubmed/31341050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00728-19
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