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Human APOBEC3G Prevents Emergence of Infectious Endogenous Retrovirus in Mice

Endogenous retroviruses (ERV) are found throughout vertebrate genomes, and failure to silence their activation can have deleterious consequences on the host. Mutation and subsequent disruption of ERV loci is therefore an indispensable component of the cell-intrinsic defenses that maintain the integr...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Treger, Rebecca S., Tokuyama, Maria, Dong, Huiping, Salas-Briceno, Karen, Ross, Susan R., Kong, Yong, Iwasaki, Akiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798113/
https://ncbi.nlm.nih.gov/pubmed/31341050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00728-19
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