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Human APOBEC3G Prevents Emergence of Infectious Endogenous Retrovirus in Mice

Endogenous retroviruses (ERV) are found throughout vertebrate genomes, and failure to silence their activation can have deleterious consequences on the host. Mutation and subsequent disruption of ERV loci is therefore an indispensable component of the cell-intrinsic defenses that maintain the integr...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Treger, Rebecca S., Tokuyama, Maria, Dong, Huiping, Salas-Briceno, Karen, Ross, Susan R., Kong, Yong, Iwasaki, Akiko
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798113/
https://ncbi.nlm.nih.gov/pubmed/31341050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00728-19
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