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Human APOBEC3G Prevents Emergence of Infectious Endogenous Retrovirus in Mice

Endogenous retroviruses (ERV) are found throughout vertebrate genomes, and failure to silence their activation can have deleterious consequences on the host. Mutation and subsequent disruption of ERV loci is therefore an indispensable component of the cell-intrinsic defenses that maintain the integr...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Treger, Rebecca S., Tokuyama, Maria, Dong, Huiping, Salas-Briceno, Karen, Ross, Susan R., Kong, Yong, Iwasaki, Akiko
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798113/
https://ncbi.nlm.nih.gov/pubmed/31341050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00728-19
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