BML-265 and Tyrphostin AG1478 Disperse the Golgi Apparatus and Abolish Protein Transport in Human Cells

The steady-state localization of Golgi-resident glycosylation enzymes in the Golgi apparatus depends on a balance between anterograde and retrograde transport. Using the Retention Using Selective Hooks (RUSH) assay and high-content screening, we identified small molecules that perturb the localizati...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Boncompain, Gaelle, Gareil, Nelly, Tessier, Sarah, Lescure, Aurianne, Jones, Thouis R., Kepp, Oliver, Kroemer, Guido, Del Nery, Elaine, Perez, Franck
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797785/
https://ncbi.nlm.nih.gov/pubmed/31681765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00232
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