The oncolytic compound LTX-401 targets the Golgi apparatus

LTX-401 is an oncolytic amino acid derivative with potential immunogenic properties. Here, we demonstrate that LTX-401 selectively destroys the structure of the Golgi apparatus, as determined by means of ultrastructural analyses and fluorescence microscopic observation of cells expressing Golgi-targ...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Zhou, Heng, Sauvat, Allan, Gomes-da-Silva, Lígia C, Durand, Sylvère, Forveille, Sabrina, Iribarren, Kristina, Yamazaki, Takahiro, Souquere, Sylvie, Bezu, Lucillia, Müller, Kevin, Leduc, Marion, Liu, Peng, Zhao, Liwei, Marabelle, Aurélien, Zitvogel, Laurence, Rekdal, Øystein, Kepp, Oliver, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136493/
https://ncbi.nlm.nih.gov/pubmed/27588704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.86
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