The oncolytic peptide LTX-315 triggers immunogenic cell death

LTX-315 is a cationic amphilytic peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis. Based on the observation that intratumorally injected LTX-315 stimulates a strong T lymphocyte-mediated anticancer immune re...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhou, H, Forveille, S, Sauvat, A, Yamazaki, T, Senovilla, L, Ma, Y, Liu, P, Yang, H, Bezu, L, Müller, K, Zitvogel, L, Rekdal, Ø, Kepp, O, Kroemer, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823948/
https://ncbi.nlm.nih.gov/pubmed/26962684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.47
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