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The oncolytic peptide LTX-315 triggers immunogenic cell death
LTX-315 is a cationic amphilytic peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis. Based on the observation that intratumorally injected LTX-315 stimulates a strong T lymphocyte-mediated anticancer immune re...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823948/ https://ncbi.nlm.nih.gov/pubmed/26962684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.47 |
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