Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis

Translation fidelity is the limiting factor in the accuracy of gene expression. With an estimated frequency of 10(−4), errors in mRNA decoding occur in a mostly stochastic manner. Little is known about the response of higher eukaryotes to chronic loss of ribosomal accuracy as per an increase in the...

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Bibliografski detalji
Izdano u:Commun Biol
Glavni autori: Shcherbakov, Dmitri, Teo, Youjin, Boukari, Heithem, Cortes-Sanchon, Adrian, Mantovani, Matilde, Osinnii, Ivan, Moore, James, Juskeviciene, Reda, Brilkova, Margarita, Duscha, Stefan, Kumar, Harshitha Santhosh, Laczko, Endre, Rehrauer, Hubert, Westhof, Eric, Akbergenov, Rashid, Böttger, Erik C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797716/
https://ncbi.nlm.nih.gov/pubmed/31637312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0626-9
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