Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis

Translation fidelity is the limiting factor in the accuracy of gene expression. With an estimated frequency of 10(−4), errors in mRNA decoding occur in a mostly stochastic manner. Little is known about the response of higher eukaryotes to chronic loss of ribosomal accuracy as per an increase in the...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Commun Biol
Autori principali: Shcherbakov, Dmitri, Teo, Youjin, Boukari, Heithem, Cortes-Sanchon, Adrian, Mantovani, Matilde, Osinnii, Ivan, Moore, James, Juskeviciene, Reda, Brilkova, Margarita, Duscha, Stefan, Kumar, Harshitha Santhosh, Laczko, Endre, Rehrauer, Hubert, Westhof, Eric, Akbergenov, Rashid, Böttger, Erik C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797716/
https://ncbi.nlm.nih.gov/pubmed/31637312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0626-9
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi