Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis

Translation fidelity is the limiting factor in the accuracy of gene expression. With an estimated frequency of 10(−4), errors in mRNA decoding occur in a mostly stochastic manner. Little is known about the response of higher eukaryotes to chronic loss of ribosomal accuracy as per an increase in the...

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Библиографические подробности
Опубликовано в: :Commun Biol
Главные авторы: Shcherbakov, Dmitri, Teo, Youjin, Boukari, Heithem, Cortes-Sanchon, Adrian, Mantovani, Matilde, Osinnii, Ivan, Moore, James, Juskeviciene, Reda, Brilkova, Margarita, Duscha, Stefan, Kumar, Harshitha Santhosh, Laczko, Endre, Rehrauer, Hubert, Westhof, Eric, Akbergenov, Rashid, Böttger, Erik C.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797716/
https://ncbi.nlm.nih.gov/pubmed/31637312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0626-9
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