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Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver
ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate metabolism highly expressed in liver, metabolizes 10-formyltetrahydrofolate to produce tetrahydrofolate (THF). This reaction might have a regulatory function towards reduced folate pools, de novo purine biosynthesis, and the flux...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6797707/ https://ncbi.nlm.nih.gov/pubmed/31624291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51397-1 |
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